Sunday, June 18

Opening plenary session
Gert Desmet Current state and future directions in liquid chromatography
Zoltán Takáts Ambient and LC-MS lipidomic profiling of clinical samples - new era in cancer diagnostics
Pat Sandra The LC toolbox for protein biopharmaceutical characterization
Peter A. Willis Searching for Life on Ocean Worlds with Liquid Phase Separation Systems

Thursday, June 22

Closing plenary session
Alberto Cavazzini Ultrafast chiral separations on modern chiral stationary phases: considerations on the impact of the particle geometry on the kinetic performance of the column
Norman J. Dovichi Capillary electrophoresis as a tool for bottom-up proteomics
Doo Soo Chung Sample preconcentration techniques in-line coupled with capillary electrophoresis-mass spectrometry

Alberto Cavazzini

University of Ferrara, Ferrara, Italy

Alberto Cavazzini has a master degree in Chemistry and received his PhD in Chemical Sciences from the University of Ferrara in 2000. He was a fellow researcher at the University of Tennessee (Knoxville, TN, USA) and Oak Ridge National Laboratories (Oak Ridge, TN, USA) from 2000 to 2002, in the group of Prof. Georges Guiochon. In 2002, he returned to Italy after accepting an Assistant Professor position at the University of Ferrara, which he held until 2014 when he became Professor of Analytical Chemistry at the same university.  Since 2015, he is a Director of graduate and undergraduate programs in Chemistry of the University of Ferrara.

His research activities focus on the field of separation science, particularly in liquid chromatography and chromatographic-like techniques. They include a variety of theoretical, experimental and applied aspects of linear and nonlinear (preparative) liquid chromatography, reaction chromatography, affinity chromatography, chiral chromatography, stationary phase characterization and development, investigation of mass transfer processes in porous media, study of retention mechanisms from both a microscopic-probabilistic and macroscopic point of view, modeling of chromatographic retention and, more recently, flow-chemistry and heterogeneous catalysis.

He is the author and co-author of some one hundred papers on peered journals, 6 book chapters and 1 patent and he has lectured extensively on local national and international levels. He is a member of the Editorial Advisory Board of Chromatographia and he has been the Guest Editor of the special issue in the Journal of Chromatography A titled “Theoretical and practical aspects in the separation of large biomolecules" (vol. 1218).

Doo Soo Chung

Seoul National University, Seoul, South Korea

Doo Soo Chung is a professor of analytical chemistry at the Department of Chemistry, Seoul National University, where he obtained a BS degree in 1981 and an MS degree in 1983 majoring in theoretical chemistry. Then he obtained an AM degree in physics in 1986 and a PhD degree in 1991 in chemical physics at Harvard University, working on nonequilibrium liquid interfaces. During his postdoctroal researche at MIT and Harvard Medical School, Chung worked on biophysics. After being appointed as an assistant professor at Seoul National University, Chung got one year training in analytical chemistry at Iowa State University. Afterwards, he has been working on a variety of topics ranging from chemical physics to bioanalytical chemistry. His group has demonstrated molecule optics that controls the molecular motions by mechanical forces of light, especially optical force chromatography separating neutral molecules. Another major research area is to improve the sensitivity of capillary electrophoresis, especially by using in-line coupled microextraction techniques for sample cleanup and preconcentration. Few examples are single drop microextraction, in-tube microextraction, and single bubble microextraction.

Gert Desmet

Vrije Universiteit Brussel, Belgium

Gert Desmet (°1967) has a Masters degree in chemical engineering and obtained his PhD in chemical engineering (fermentation technology) from the Vrije Universiteit Brussel (VUB), Brussels, Belgium, where he currently is a full professor in chemical engineering and heads the Department of Chemical Engineering. In 2012-2015, he was the vice-dean of the Faculty of Sciences and Bioengineering.

His research focuses on the miniaturization of separation methods and on the investigation and the modeling of flow effects in chromatographic systems. He is a past co-chair and chair of the Chemistry Panel of the Belgian National Science Fund (FWO) and is an Associate Editor of the journal Analytical Chemistry. In 2016, his research was rewarded with an ERC Advanced Grant.

Up to date, he has been the promoter of 28 successfully finished PhDs and has been authoring over 250 peer reviewed papers in international peer-reviewed journals and 11 patent applications. He is a member of the editorial advisory board of J Chrom A and LC-GC magazine and a member of the permanent scientific committee of the "International Symposium on Chromatography (ISC)”, as well as of the SCM and HTC conference series.

He and his students presented over 250 lectures at international conferences and symposia in the past 10 years and have received numerous awards for their oral or poster presentations, including Nanotech Montreux, and HTC conference and HPLC conference series. In 2006, he received the Desty Memorial award. In 2008, he received the “Emerging Leader in Chromatography”-award from LC-GC North America and the "Agilent Technologies Award" from the Agilent Technologies foundation. In 2009, he received the Silver Jubilee Medal of the Chromatographic Society of the UK.

Norman J. Dovichi

University of Notre Dame, Indiana, USA

Norman J. Dovichi received his PhD in Physical/Analytical Chemistry from the University of Utah, where he was Joel Harris’s first graduate student. He spent 18 months at Los Alamos Scientific Laboratory as a postdoctoral fellow, where he worked in both the Biophysics and Physical Chemistry programs. He has held faculty positions at the Universities of Wyoming, Alberta, and Washington before taking his current position at the University of Notre Dame.

His research interests have spanned a wide range of topics. His early career focused on the use of lasers in chemical analysis, and he was an early pioneer in single molecule analysis. In 1987, his group coupled capillary electrophoresis with laser-based detectors for ultrasensitive analysis. That work evolved into the development of high throughput capillary array electrophoresis for DNA sequence analysis, which played a seminal role in the human genome sequencing project. In parallel, his group developed a suite of tools based on one- and two-dimensional capillary electrophoresis for characterization of proteins and metabolites within single eukaryotic cells. Over the past decade, his group has worked to couple capillary zone electrophoresis to electrospray mass spectrometry. These tools have been used to perform bottom-up and top-down analysis of eukaryotic and prokaryotic proteomes. Finally, he has developed a program in proteomics of early stage vertebrate embryos. This project generated the first comprehensive measurement of protein expression in single Xenopus zygotes, and the first quantitative study of changes in protein expression across early stages of the development of that organism.

He has supervised the completion of 60 PhD degrees and has authored over 275 papers. He has served as an associate editor of Analytical Chemistry since 2003. He has held an honorary professorship from the Chinese Academy of Sciences since 2002. He has presented over 500 invited talks at conference, Universities, and industrial and government laboratories.

Pat Sandra

Research Institute for Chromatography, Kortrijk, Belgium

Pat J. Sandra received his Master's degree in Organic Chemistry in 1969 followed by a Ph.D. degree in Analytical Chemistry in 1975 from the Ghent University, Belgium. He joined the Faculty of Sciences at the Ghent University in 1976 as Assistant Professor and was promoted to Full Professor in 1988. In 1986 he founded the Research Institute for Chromatography (RIC) in Belgium, a center of excellence for research and education in chromatography, mass spectrometry and capillary electrophoresis. End 2011 he retired from the Ghent University and is presently spending most of his time at RIC. He was extraordinary professor at the Eindhoven University of Technology, The Netherlands (1991-2000) and at the University of Stellenbosch, South Africa (1998-2013). He was Co-founder of the Pfizer Analytical Research Center (PARC) that he directed during the period 2003-2011. In 2013 he was appointed member of the Research Council of President Barroso of the European Community.

He has authored or co-authored over 500 peer-reviewed scientific publications, 25 chapters in books and presented over 350 invited lectures at scientific meetings. He has been active in all fields of separation science (capillary GC, LC, SFC and CE) and in mass spectrometry. His present interest is focused on high resolution techniques for the characterization of biopharmaceuticals, implementation of these techniques in QA/QC and GMP environments and on automation in sample preparation.

Among numerous awards are the American Chemical Society Chromatography Award (2005), Doctor Honoris Causa in Pharmaceutical Sciences (2004, Turin, Italy), Doctor Honoris Causa in Food Safety (2007, Messina, Italy), Honorary Professor at the Dalian Institute for Chemical Physics, Chinese Academy of Sciences (2007) and Doctor Honoris Causa in Chemistry (2012, Bucharest, Romania). 

Zoltán Takáts

Imperial College, London, UK

Professor Zoltan Takats obtained his PhD from Eötvös Loránd University, Budapest, Hungary.  He has worked as a post-doctoral research associate at Purdue University, Indiana, USA. After returning to Hungary, he served as Director of Cell Screen Research Centre and also as Head of Newborn Screening and Metabolic Diagnostic Laboratory at Semmelweis University, Budapest. Professor Takats was awarded the Starting Grant by the European Research Council in 2008 and he subsequently was appointed to a Junior Research Group Leader at Justus Liebig University, Gießen, Germany.  He moved to the United Kingdom in 2012 and is currently a Professor of Analytical Chemistry, Director of Mass Spectrometry Research within Division of Computational Systems and Medicine, Deputy Head of Division of Computational Systems and Medicine. He has published over 100 peer-reviewed articles in the fields of analytical chemistry and translational medicine, with more than 3000 independent citations. Some of these were published in Science, Nature, PNAS and Angewandte Chemie International Edition. He is primary inventor of eight analytical methods including Desorption Electrospray Ionization and Rapid Evaporative Ionization Mass Spectrometry, which are commercially available from Prosolia Inc. and Waters Corporation. He is one of the founders of the field termed ‘Ambient Ionization Mass Spectrometry’. He was also the recipient of the prestigious Mattauch-Herzog Award of the German Mass Spectrometry Society and the Hungarian Star Award for Outstanding Innovators.

Peter A. Willis

NASA, Pasadena, USA

Dr. Peter Willis received his Ph.D. degree from Cornell University in 1999.  As the first graduate student in laboratory of H. Floyd Davis, he designed, built and validated the first crossed molecular beams machine with a rotating source for the study of neutral transition metal atom reactions. Following his graduate work he moved to the laboratory of Richard E. Smalley at Rice University, where he developed and validated a method and instrument system for the mass-production of single-walled carbon nanotubes.  In 2001 he continued his postdoctoral research in nanotechnology at Caltech with collaborator James Heath.  While at Caltech he was part of a new research effort to develop nanobiosensors for real-time proteomics.  In 2004 he joined the technical staff at the nearby Jet Propulsion Laboratory, operated by Caltech for NASA, in order to advance the development of the Urey Instrument, intended for the European ExoMars rover mission.  Since the cancellation of that project in 2009, Dr. Willis has lead his own research group in microfluidic chemical analysis for robotic astrobiology missions to other worlds, and participated in the development of a variety of analytical chemistry instruments in various stages of technology readiness level. He is currently a member of the Science Office for the Mars 2020 Rover Mission, serving as the Investigation Scientist for the SuperCam Instrument suite.  Beyond Mars, he is also funded is to develop microfluidic chemical analysis systems that digest a range of different sample types from their environment, on missions even further in the future.  So in addition to developing the first rover-mounted fully autonomous microchip electrophoresis instrument for deployment in the Atacama Desert of Chile in 2017-2019, he is also developing cryogenic vacuum capable systems for use on future missions to the icy worlds of Europa and Enceladus, in the outer solar system.

Symposium secretariat: C-IN, 5. kvetna 65, 140 21 Prague 4, Czech Republic | tel.: +420 261 174 305
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